Synthetic Biology

Synthetic biology leading to advancements in sustainable practices and biomanufacturing capabilities is an important focus area of WRCB. Here is a list of synthetic biology projects supported by WRCB.
9th Call

Platform technology for the production of high-value recombinant proteins in E. coli

Developed By

Pramod Wangikar

Department

Chemical Engineering

9th Call

Biocatalysis towards industry scale synthesis of isoindolone drug derivatives

Developed By

Debabrata Maiti

Department

Chemistry

4th Call

A central strategy for expeditious synthesis of bioactive flavans

Developed By

Santosh Gharpure

Department

Chemistry

3rd Call

Development of technology package for alcohol dehydrogenases (ADH) - catalyzed synthesis of chiral alcohols

Developed By

Pramod Wangikar

Department

Chemical Engineering

1st Call

Structural and Biochemical characterization of regulatory proteins useful in developing biosensors for water purification system

Developed By

Ruchi Anand

Department

Chemistry

1st Call

Microalgal CO2 capture process: Design and testing at a power plant site

Developed By

Pramod Wangikar, John Beardall, Manaswita Bose

Department

Chemical Engineering, Monash University, Energy Science and Engineering

Tuning the bacterial system for high production of Super vitamin Coenzyme Q10

Developed By

Ashutosh Kumar

Department

Biosciences and Bioengineering

Development of a cell-free platform for detection of bacterial virulence factors and protein synthesis

Developed By

Ishita Sengupta

Department

Chemistry

Bioenergy with carbon capture and storage (BECCS)

Developed By

Arnab Dutta & Vikram Vishal

Department

Chemistry, Biosciences and Bioengineering

Evaluation of indigenously developed CAR-T platform technology for the treatment of acute lymphoblastic leukemia (ALL)

Developed By

Rahul Purwar

Department

Biosciences and Bioengineering

Development Of Cell Culture System That Will Facilitate Expansion Of Human Mesenchymal Stem Cells Without Sacrificing Their Stemness

Developed By

Abhijit Majumder

Department

Chemical Engineering

eRapid: Multiplexed Electrochemical Sensors for Fast, Accurate, Portable Diagnostics

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synthetic-biology

Crisscross Nanoseed Detection: Nanotechnology-Powered Infectious Disease Diagnostics

This nanotech-based diagnostic platform uses a unique nucleation mechanism that assembles a DNA "nanoseed" in the presence of a pathogen-derived biomarker that then is amplified within 15 minutes to create a signal for easy detection. It is highly robust, and cost-effective, and can be adapted to detect a variety of biomarkers.
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wFDCF Face Masks: A Wearable COVID-19 Diagnostic

The Problem The COVID-19 pandemic has made it starkly clear that the world lacks rapid, accurate diagnostic tests for pathogens. When patients arrive in a medical facility for treatment, the triage process is hindered by diagnostic tests that are inaccurate or take a long time to produce results
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